Genetically modifying transcription factors to promote CNS axon regeneration
نویسندگان
چکیده
منابع مشابه
Modifying lipid rafts promotes regeneration and functional recovery.
Ideal strategies to ameliorate CNS damage should promote both neuronal survival and axon regeneration. The receptor Neogenin promotes neuronal apoptosis. Its ligand prevents death, but the resulting repulsive guidance molecule a (RGMa)-Neogenin interaction also inhibits axonal growth, countering any prosurvival benefits. Here, we explore strategies to inhibit Neogenin, thus simultaneously enhan...
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عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2017